An iterative process produces oxamniquine derivatives that kill the major species of schistosomes infecting humans
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چکیده
منابع مشابه
Genotypes of Cryptosporidium species infecting fur-bearing mammals differ from those of species infecting humans.
Of 471 specimens examined from foxes, raccoons, muskrats, otters, and beavers living in wetlands adjacent to the Chesapeake Bay, 36 were positive for five types of Cryptosporidium, including the C. canis dog and fox genotypes, Cryptosporidium muskrat genotypes I and II, and Cryptosporidium skunk genotype. Thus, fur-bearing mammals in watersheds excreted host-adapted Cryptosporidium oocysts that...
متن کاملIntrogressed Animal Schistosomes Schistosoma curassoni and S. bovis Naturally Infecting Humans
net) with the maximum-likelihood algorithm and a boot-strap of 1,000 replicates, we constructed a phylogenetic tree (online Technical Appendix Figure). All 8 sequences clustered within subtype 4d of HEV. The sequences were similar to each other (95.5%–99.8% similarity in nucleotide sequence) and similar to sequences reported for other cattle (83.3%–85.3%; online Technical Appendix Figure). More...
متن کاملKilling of Leishmania parasites in activated murine macrophages is based on an L-arginine-dependent process that produces nitrogen derivatives.
The experiments described in this report were aimed at determining whether L-arginine (L-arg)-derived nitrogen oxidation products (nitric oxide, nitrous acid, nitrites) are involved in the intracellular killing of Leishmania parasites by activated murine macrophages in vitro. Peritoneal or bone marrow-derived macrophages were infected with L. enriettii or L. major, then activated by exposure to...
متن کاملContemporary status of insecticide resistance in the major Aedes vectors of arboviruses infecting humans
Both Aedes aegytpi and Ae. albopictus are major vectors of 5 important arboviruses (namely chikungunya virus, dengue virus, Rift Valley fever virus, yellow fever virus, and Zika virus), making these mosquitoes an important factor in the worldwide burden of infectious disease. Vector control using insecticides coupled with larval source reduction is critical to control the transmission of these ...
متن کاملAn Iterative Tâtonnement Process
A discrete time tâtonnement process is presented for reaching an equilibrium of an exchange economy. The process is based on updating the prices in proportion to excess demands of the commodities such that the new prices are positive and their changes are bounded. Global convergence conditions for the process are given and convergence is shown when the excess demand function has the gross subst...
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ژورنال
عنوان ژورنال: PLOS Neglected Tropical Diseases
سال: 2020
ISSN: 1935-2735
DOI: 10.1371/journal.pntd.0008517